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Our Mission

The Michigan Nanotechnology Institute for Medicine and Biological Sciences is a true multidisciplinary team of chemists, physicists, engineers, toxicologists, physicians, biologists, pharmacists, and (bio)informatics specialists collaborating on nanoscience in biology and medicine. The Institute involves approximately 60 faculty in a "no-walls" model using facilities in the Engineering, Medical and LS&A schools to enhance competitiveness for externally funded grants and contracts.

We have three goals:

~  First, to facilitate interaction among diverse scientific disciplines to accelerate discovery in Nanomedicine.

~  Second, to foster translational science with the goal to commercialize our discoveries.

~  Third, to fulfill our educational mission to build a multidisciplinary Rackham Graduate School Certificate program in Nanobiology, and to design a minor in Nanobiology for undergraduate students.

Students: see our nanobiology graduate program.

BlueLine

Current News and Events:

Tuesday, August 31st at 9:30 am, Daniel McNerny defends his thesis "DENDRON AVIDITY PLATFORMS WITH ORTHOGONAL FOCAL POINT COUPLING SITE." See abstract.

Medical Science II Building, North Lecture Hall.

Chair: James R. Baker, Jr., M.D.

August 2010, The Defense Advanced Research Project Agency awarded a multidisiplinary team of scientisits at MNIMBS $2M to work on development of controlled extended release of analgesics for battlefield application. The faculty team consists of Principal Investigator, James R. Baker Jr, the Ruth Dow Doan Professor of Internal Medicine and Director of MNIMBS, Abraham F. L. Vanderspek, M.D., associate professor of anesthesiology; Brent Ward, MD, DDS, FACS, assistant professor of oral and maxillofacial surgery and program director of Oncologic Maxillofacial/Head & Neck Surgery; Thommey P. Thomas, Ph.D., research assistant professor, Department of Internal Medicine and MNiIMBS, X Baohua Huang, Ph.D., research investigator in the Department of Internal Medicine and MNIMBS, Seok Ki Choi, Ph.D., research assistant professor, Department of Internal Medicine and MNIMBS; Yuehua Zhang, Ph.D., research assistant professor in the Department of Internal Medicine and MNIMBS.

Monday June 21, 2010, 4-5 PM, Ashutosh Chilkoti, Ph.D., Theo Pilkington Professor of Biomedical Engineering, Center for Biologically Inspired Materials and Materials Systems, Department of Biomedical Engineering, Duke University, will give a Doan lecture: Protein-Polymer Nanoparticles
for Delivery of Therapeutics

May 2010 Douglas Mullen defended his thesis entitled: Design of Multi-functional Drug Delivery Platforms and earned his Ph.D. in Macromolecular Science and Engineering – The University of Michigan, Ph.D. completed May 2010, conferred August 2010; Advisor – Professor Mark M. Banaszak Holl. 

May 2010, Yunbo Guo defended his thesis and earned his Ph.D. degree in Electrical Engineering with a Nanobiology Certificate, University of Michigan, Ann Arbor
Thesis: Sensitive, label-free biomolecular binding detection using a one-dimensional photonic crystal sensor. Chair: Professor Theodore B. Norris

Monday March 29, 2010, 4-5 PM, Tarek M. Fahmy, Ph.D., Associate Professor, Biomedical Engineering, Yale University, will give a Doan Lecture: Biomimetic Approaches to Modulating the Immune Response with Biodegradable Polymers

On January, 24, 2010, Yunbo Guo, MNIMBS PhD student, will be awarded the Newport Spectra-Physics Research Excellence Travel Grant at the Moscone Center. The work is based on detection of small molecules which is an inherently difficult application for "label-free" optical sensors. "Success in this area would be a significant advance."

November 8, 2009: Know The Nanotechnology Movement. PC Laptop Shop.

October 15, 2009: UM MNIMBS and NanoBio get $9.4M new grant injection for adjuvant work. See John Carrol's article in Fierce Vaccines

October 15, 2009: NanoBio reports good results on cystic fibrosis studies. By Tom Henderson Crain's Detroit Business

October 15, 2009: Research and Markets: Dendrimer-Based Nanomedicine: Essential Book for Those Involved in Nanotechnology, Macromolecular Science, Cancer Therapy or Drug Delivery Research Earth Times

September 28, 2009: Nanotech battlefield treatment to ease pain and limit dangerous side effects By Jeff Salton Gizmag

September 21, 2009: 2 - 5:45 PM, The Herbert D. Doan Nanotechnology Symposium

September 15, 2009: Introducing Nanoemulsion Lotion for Treatment of Severe Burns. R & D Magazine

September 14, 2009: Nanotechnology treatment for burns reduces infection, inflammation Nanotechnology treatment for burns reduces infection, inflammation. InSciences Organisation

August 17, 2009: NanoBio to Present Preclinical Data on its Novel, Nanoemulsion-based Vaccine Adjuvant Platform at the Immunotherapeutics & Vaccine Summit. PharmaLive

This is an example of successful translation of research. The intranasal nanoemulsion-adjuvanted influenza vaccine that NanoBio Corp. now has in Phase I studies was originally developed at MNIMBS.

August 16, 2009: UM researcher aims to treat CF through nanoemulsion tech. By Ryan Beene Crain's Detroit Business

February 9, 2009: 8:30am, Chis V. Kelly will do his Final Oral Examination for his thesis: "The Biophysics of nanoparticles interacting with the plasma membrane."

Location: BSRB 1130-C.

Chair: Professor Brad Orr

January 19, 2009:  Other Voices: U-M can take the lead in combating disease with technology

by John Prensner, Maggie Kober and Adam Castano in Mlive.com  Maggie Kober is now a 2nd year medical student at UofM and is a former undergrad in MNiMBS for 3.5 years.

January 5, 2009: Mark Banaszak Holl, professor of chemistry and of macromolecular science and engineering at the University of Michigan, was elected as a fellow of American Association for the Advancement of Science (AAAS).

"Banaszak Holl studies the development of polymer-based drug transport agents and their interactions with lipid bilayers, organelles and cells. He was honored by AAAS for distinguished contributions bridging disciplinary boundaries in studies of chemical and biochemical processes at the nanoscale." The University Record.

Tuesday, December 2, 2008; 2:30 PM, Paul Edward Makidon will do his Final Oral Examination for his thesis

OIL-IN-WATER NANOEMULSIONS AS MUCOSAL VACCINE ADJUVANTS:
CHARACTERIZATION, MECHANISM, FORMULATION, AND DEVELOPMENT OF A
NANOEMULSION-BASED BURKHOLDRERIA CENOCEPACIA VACCINE

Location: 1170A and 1150B BSRB
Chair: Professor James R. Baker, Jr.

August 13, 2008 Nano vaccine for hepatitis B produces strong immunity

April 21 , 2008 - Dr. James R. Baker Jr. has been named the Distinguished University Innovator for 2008.

Baker, a scientist in the Medical School and a successful entrepreneur, has conducted breakthrough research in nanotechnology materials and launched two startup companies based on the results.

On Monday afternoon, March 31, 2008, we held our endowed Nanotechnology Symposium named in honor of one of our benefactors, Mr. Herbert D. Doan, the former Chairman of the Dow Chemical Company. The program featured speakers who reflect the cross-disciplinary nature of the Institute: Charles Cantor, Ph.D. Chief Scientific Officer, Sequenom, San Diego, CA and James W. Schneider, PhD, Associate Professor of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA.  Click for further information.

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