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Mohamed E.H. El-Sayed, Ph.D.

Assistant Professor, Department of Biomedical Engineering

Dr. Mohamed E.H. El-Sayed received his bachelors and doctoral degrees in pharmaceutical sciences from Cairo University, Egypt and the University of Maryland in Baltimore, respectively. He joined the University of Michigan, Department of Biomedical Engineering in January 2007 after spending three and half years as a Senior Fellow at the University of Washington, Department of Bioengineering. Dr. El-Sayed has received several honors and awards including Coulter Foundation Translational Research Partnership in Biomedical Engineering Award (2008), the NSF-CAREER award (2008), the Susan G. Komen Breast Cancer Foundation Postdoctoral Fellowship (2005), the US Department of Defense Multidisciplinary Postdoctoral Award (2005), and the National Cancer Center Postdoctoral fellowship (2004). Dr. El-Sayed is also a member of the Rho-Chi National Pharmacy Honor Society.


Research Interests: Dr. El-Sayed’s research program focuses on the rational design and synthesis of novel polymeric carriers that can effectively "communicate" with different epithelial and endothelial barriers encountered within the body to selectively deliver their therapeutic cargo to the diseased tissues with cellular and subcellular accuracy. These optimized drug delivery systems will enhance the therapeutic activity of the incorporated drug while eliminating or minimizing its potential side effects. Our research approach is multidisciplinary in nature and utilizes a wide range of sophisticated techniques including polymer and bioconjugate chemistry, radiochemistry, cellular and molecular biology, microscopy, in vitro cell culture, and in vivo evaluation using animal models. We actively collaborate with other clinicians and basic scientists to develop innovative diagnostic and therapeutic systems that can eventually move into the clinic and produce a positive impact on patient care.


Address: Department of Biomedical Engineering

1101 Beal Ave.; Lurie Biomedical Engineering, Room 2150; Ann Arbor, MI 48109-2110

Tel: (734) 615-9404; Fax: (734) 647-4834; E-mail:



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