Ayyalusamy Ramamoorthy, Ph.D., is a Professor of Chemistry and Biophysics at the University of Michigan, Ann Arbor. He graduated from the Indian Institute of Technology, India, with a Ph.D in Chemistry in 1990. He worked as Scientist in a National Lab in India from 1989 to 1992, and worked for JEOL Ltd in Tokyo as a Scientist from 1992 to 1993. He then moved to the United States to work as a Research Associate in the NIH Biological NMR center at the University of Pennsylvania, Philadelphia (1993-1996). Dr. Ramamoorthy is a winner of the CAREER development award from NSF, Young Scientist Award from JEOL, Research Partnership Award from Eli Lilly, and a Grant-in-Aid Award from American Heart Association. He has more than 115 peer-reviewed publications, several chapters in books, and edited two books and several special issues. Over the past 12 years, Dr. Ramamoorthy¹s studies have focused on the atomistic-level high-resolution imaging of membrane-associated peptides and proteins that play important roles in diabetes, Alzheimer¹s disease, cancer, and heart diseases. Research projects in his lab utilize a variety of biophysical techniques including sophisticated NMR spectroscopy experiments.
Research interests: Our research interests involve the structure, dynamics, and function of macromolecules such as membrane-associated peptides/proteins, nanomedicine and polymorphic pharmaceutical compounds. Specific biological systems that are presently being investigated are cytochrome-b5, cytochrome-P450, membrane-disruptive peptides (such as antimicrobial peptides, amyloid peptides, and HIV fusion peptide), dendrimers, and other nanomaterials. We use a variety of biophysical techniques (but mainly solid-state NMR spectroscopy) to investigate these nano-biological systems at atomistic-level resolution.
Our expertise in applying a variety of biophysical techniques (but mainly solid-state NMR spectroscopy) to investigate these nano-biological systems at atomistic-level resolution has been a great advantage in the investigation of nanomedicines like dendrimers and their derivatives.
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