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2013 Publications


Ward BB, Huang B, Desai A, Cheng XM, Vartanian M, Zong H, Shi X, Thomas TP, Kotlyar AE, Van Der Spek A, Leroueil PR, Baker JR Jr. Sustained analgesia achieved through esterase-activated morphine prodrugs complexed with PAMAM dendrimer. Pharm Res. 2013 Jan;30(1):247-56.


Myc A, Kukowska-Latallo JF, Smith DM, Passmore C, Pham T, Wong PT, Bielinska AU, Baker JR Jr. Nanoemulsion nasal adjuvant W805EC induces dendritic cell engulfment of antigen-primed epithelial cells. Vaccine. 2013 Feb 4;31(7):1072-9. PMCID: PMC3556236


Choi SK, Myc A, Silpe JE, Sumit M, Wong PT, McCarthy K, Desai AM, Thomas TP, Kotlyar A, Holl MM, Orr BG, Baker JR Jr. Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface. ACS Nano. 2013 Jan 22;7(1):214-28.


Leung S, Smith D, Myc A, Morry J, Baker JR Jr. OT-II TCR transgenic mice fail to produce anti-ovalbumin antibodies upon vaccination. Cell Immunol. 2013 Apr;282(2):79-84.


Cline EN, Li MH, Choi SK, Herbstman JF, Kaul N, Meyhöfer E, Skiniotis G, Baker JR, Larson RG, Walter NG. Paclitaxel-conjugated PAMAM dendrimers adversely affect microtubule structure through two independent modes of action. Biomacromolecules. 2013 Mar 11;14(3):654-64. PMCID: PMC3603340


Matz RL, Erickson B, Vaidyanathan S, Kukowska-Latallo JF, Baker JR Jr, Orr BG, Banaszak Holl MM. Polyplex exposure inhibits cell cycle, increases inflammatory response, and can cause protein expression without cell division. Mol Pharm. 2013 Apr 1;10(4):1306-17. PMCID: PMC3637663


Goonewardena SN, Kratz JD, Zong H, Desai AM, Tang S, Emery S, Baker JR Jr, Huang B. Design considerations for PAMAM dendrimer therapeutics. Bioorg Med Chem Lett. 2013 May 15;23(10):2872-5. PMID:23583511


Thomas TP, Joice M, Sumit M, Silpe JE, Kotlyar A, Bharathi S, Kukowska-Latallo J, Baker JR, Choi SK. Design and In Vitro Validation of Multivalent Dendrimer Methotrexates as a Folate-targeting Anticancer Therapeutic. Curr Pharm Des. 2013;19(37):6594-605. PMCID: PMC3859140


Baker JR Jr. Why I believe nanoparticles are crucial as a carrier for targeted drug delivery. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Sep-Oct;5(5):423-9. l


Inlay MA, Choe V, Bharathi S, Fernhoff NB, Baker JR Jr, Weissman IL, Choi SK. Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. Chem Commun (Camb). 2013 May 28;49(43):4971-3. PMCID: PMC3926663


Smith DM, Simon JK, Baker JR Jr. Applications of nanotechnology for immunology. Nat Rev Immunol. 2013 Aug;13(8):592-605.

van Dongen MA, Desai A, Orr BG, Baker JR Jr, Holl MM. Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer. Polymer (Guildf). 2013 Jul 19;54(16):4126-4133. PMCID: PMC3775363


Yu S, Li MH, Choi SK, Baker JR, Larson RG. DNA condensation by partially acetylated poly(amido amine) dendrimers: effects of dendrimer charge density on complex formation. Molecules. 2013 Sep 3;18(9):10707-20.  


Chang HN, Leroueil PR, Selwa K, Gasper CJ, Tsuchida RE, Wang JJ, McHugh WM, Cornell TT, Baker JR Jr, Goonewardena SN. Profiling inflammatory responses with microfluidic immunoblotting. PLoS One. 2013 Nov 27;8(11) PMCID: PMC3842271


Passmore C, Makidon PE, O'Konek JJ, Zahn JA, Pannu J, Hamouda T, Bitko V, Myc A, Lukacs NW, Fattom A, Baker JR Jr. Intranasal immunization with W 80 5EC adjuvanted recombinant RSV rF-ptn enhances clearance of respiratory syncytial virus in a mouse model. Hum Vaccin Immunother. 2013 Dec 10;10(3).


Wong PT, Wang SH, Ciotti S, Makidon PE, Smith DM, Fan Y, Schuler CF 4th, Baker JR Jr. Formulation and Characterization of Nanoemulsion Intranasal Adjuvants: Effects of Surfactant Composition on Mucoadhesion and Immunogenicity. Mol Pharm. 2013 Dec 13.


Goonewardena SN, Leroueil PR, Gemborys C, Tahiliani P, Emery S, Baker JR, Zong H. Fluorogenic 'click-on' dendrimer reporter for rapid profiling of cell proliferation. Bioorg. Med. Chem. Lett. 2013;23(7):2230-2233 PMID:23434421


Lanza GM, Moonen C, Baker JR Jr, Chang E, Cheng Z, Grodzinski P, Ferrara K, Hynynen K, Kelloff G, Lee YE, Patri AK, Sept D, Schnitzer JE, Wood BJ, Zhang M, Zheng G, Farahani K., Assessing the barriers to image-guided drug delivery. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Jan;6(1):1-14


Wang SH, Lu L, Fan Y, Wicha MS, Cao Z, Chang AE, Xia JC, Baker JR Jr, Li Q. Characterization of a Novel Transgenic Mouse Tumor Model for Targeting HER2+ Cancer Stem Cells. Int J Biol Sci. 2013 Dec 6;10(1):25-32. PMCID: PMC3879588



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