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Wang, Suhe, MD, PhD Research Associate Professor

4037 BSRB

109 Zina Pitcher Place
Ann Arbor, MI 48109-2200
Phone: 734-615-2205
Email: shidasui@umich.edu 

Su He Wang, M.D., Ph.D., is a Research Associate Professor in the Department of Medicine. She earned her M.D. at Fujian Medical University, China, and received a Ph.D. in Pharmaceutical Sciences from the University of Strathclyde, U.K.  Her postdoctoral training was done at King's College School of Medicine, UK (with Dr. Paul Banga) and the University of Michigan (with Dr. James Baker). Her research focuses on nanomedicine, particularly novel nano-agents for infection control, cancer treatments and autoimmune therapy. Her research in the above areas has been supported by DOD, NIH, and US Thyroid Research Council. She has authored more than 58 peer-reviewed publications as well as 6 book chapters.

Representative Publications:

Wang SH, Mezosi E, Wolf JM, Cao Z, Utsugi S Gauger PG, Doherty GM, Baker JR Jr.  IFNg sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by up-regulating Bak expressionOncogene, 2004;23:928-935 

 Wang SH, Shi X, Van Antwerp M, Cao Z, Swanson SD, Bi  X, Baker JR Jr.  Dendrimer-Functionalized Iron Oxide Nanoparticles for Specific Targeting and Imaging of Cancer CellsAdv  Func  Mater,  2007;17:3043-3050.

Wang SH*, Chen GH, Fan YY, Van Antwerp M, Baker JR Jr.  TRAIL inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+regulatory T cellsEndocrinology,  2009;150 (4):2000-2007.  PMCID:  PMC2659286

Shi X, Lee I, Chen X, Shen M, Xiao S, Baker JR Jr., Wang SH*.  Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimersSoft Matter, 2010 Jan; 1(6):2539-2545.  PMCID: PMC2941193.

Wang SH*, Fan YY, Makidon  PE, Cao Z, Baker JR Jr. Induction of immune tolerance in mice with a novel mucosal nanoemulsion adjuvant and self-antigen. Nanomedicine, 2012, 7(6):867-876. PMID:  22420425.

Wang SH*, Lu L, Fan Y, Wicha MS, Cao Z, Chang AE, Xia JC, Baker JR Jr, Li Q. Characterization of a novel transgenic mouse tumor model for targeting HER2+ cancer stem cells. Int J Biol Sci, 2013 Dec 6;10(1):25-32. PMCID: PMC3879588

Wong PT, Wang SH, Ciotti S, Makidon PE, Smith DM, Fan Y, Schuler IV CF, Baker JR Jr. Formulation and characterization of nanoemulsion intranasal adjuvants: effects of surfactant composition on mucoadhesion and immunogenicity.   Mol Pharmaceutics, 2014, 11(2): 531−544. PMCID: PMC4031264

Wang SH*, Fan Y, Baker JR Jr. Overexpression of BID in thyroids oftransgenic mice increases sensitivity to iodine-induced autoimmune thyroiditis. J Transl Med, 2014 June 23; 12:180 PMCID:  PMC4083877

Otis1 J, Zong H,, Kotylar A., Yin A., Bhattacharjee S, Wang H., Baker JR Jr., Wang SH * Dendrimer Antibody Conjugate to Target and Image HER-2 Overexpressing Cancer Cells . Oncotarget, 2016 June 14; 7(24):36002-36013. PMCID: PMC5094978 

Fan Y, Ciotti S, Cao Z, Eisma R, Baker JR Jr, Wang SH*.  Screening of nanoemulsion formulations and identifications of NB-201 as an effective topical antimicrobial for staphylococcus aureaus in a mouse model of infected woundsMill Med, 2016 May; 1815: 259-264.

Book Chapters:

Wang SH, Baker Jr JR. Immunopathogenesis of Thyroiditis. In:  Immunoendocrinology: Scientific and Clinical Aspects. George S Eisenbarth (ed.), Springer Publishers, 443-456, 2011.

Wang SH, Baker JR Jr. Apoptosis in thyroid cancer. In: Thyroid Cancer: A comprehensive guide to clinical management, 3nd Edition, 55-62, 2011.